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2017年代表论文

1.     Liu YQ, Lai SR, Ma WN, Ke W, Zhang C, Liu SM, Zhang Y, et al. CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression. Nature Communications 2017;8.

2.     Bu QX, Li ZQ, Zhang JY, Xu F, Liu JM, Liu HL. The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins. Journal of Biological Chemistry 2017;292:16055-16069.

3.     Cao MN, Wang HX, Guo LM, Yang SM, Liu C, Khor TO, Yu SW, et al. Dibenzoylmethane Protects Against CCl4-Induced Acute Liver Injury by Activating Nrf2 via JNK, AMPK, and Calcium Signaling. Aaps Journal 2017;19:1703-1714.

4.     Cheng W, Liu Z, Yu Y, van Ofwegen L, Proksch P, Yu SW, Lin WH. An unusual spinaceamine-bearing pregnane from a soft coral Scleronephthya sp inhibits the migration of tumor cells. Bioorganic & Medicinal Chemistry Letters 2017;27:2736-2741.

5.     Gao XL, Sun Q, Zhang WW, Jiang YM, Li RT, Ye J. Anti-inflammatory effect and mechanism of the spirocyclopiperazinium salt compound LXM-15 in rats and mice. Inflammation Research 2018;67:363-370.

6.     Ji LY, Yang SM, Li SS, Liu S, Tang SN, Liu ZQ, Meng XB, et al. A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes. Oncotarget 2017;8:37394-37408.

7.     Ji S, Tang SN, Li K, Li ZW, Liang WF, Qiao X, Wang Q, et al. Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy. Toxicology and Applied Pharmacology 2017;326:25-33.

8.     Li W, Liu HH, Jiang HJ, Wang C, Guo YF, Sun Y, Zhao X, et al. (S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Scientific Reports 2017;7.

9.     Lin SW, Li YB, Zheng YF, Luo LC, Sun Q, Ge ZM, Cheng TM, et al. Design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs. European Journal of Medicinal Chemistry 2017;127:442-458.

10.   Lin ZH, Liu JM, Ding HD, Xu F, Liu HL. Structural basis of SALM5-induced PTP delta dimerization for synaptic differentiation. Nature Communications 2018;9.

11.   Liu RZ, Fan CX, Zhang ZL, Zhao X, Sun Y, Liu HH, Nie ZX, et al. Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging. International Journal of Molecular Sciences 2017;18.

12.   Liu T, Jia PP, Ma HL, Reed SA, Luo XZ, Larman HB, Schultz PG. Construction and Screening of a Lentiviral Secretome Library. Cell Chemical Biology 2017;24:767-+.

13.   Liu XY, Chen XL, Zhu YJ, Wang KW, Wang YY. Effect of magnolol on cerebral injury and blood brain barrier dysfunction induced by ischemia-reperfusion in vivo and in vitro. Metabolic Brain Disease 2017;32:1109-1118.

14.   Peng H, Bian XL, Ma FC, Wang KW. Pharmacological modulation of the voltage-gated neuronal Kv7/KCNQ/M-channel alters the intrinsic excitability and synaptic responses of pyramidal neurons in rat prefrontal cortex slices. Acta Pharmacologica Sinica 2017;38:1248-1256.

15.   Wang W, Zhao Z, Zhang Z, Zhang C, Xiao S, Ye X, Zhang L, et al. Redirecting Killer T Cells through Incorporation of Azido Sugars for Tethering Ligands. Chembiochem 2017;18:2082-2086.

16.   Wang Y, Wu X, Du M, Chen X, Ning X, Chen H, Wang S, et al. Eg5 inhibitor YL001 induces mitotic arrest and inhibits tumor proliferation. Oncotarget 2017;8:42510-42524.

17.   Wu L, Chen J, Wu Y, Zhang B, Cai X, Zhang Z, Wang Y, et al. Precise and combinatorial PEGylation generates a low-immunogenic and stable form of human growth hormone. J Control Release 2017;249:84-93.

18.   Yao T, Zhou X, Zhang C, Yu X, Tian Z, Zhang L, Zhou D. Site-Specific PEGylated Adeno-Associated Viruses with Increased Serum Stability and Reduced Immunogenicity. Molecules 2017;22.

19.   Zhang CL, Lu JQ, Su HZ, Yang J, Zhou DM. Fatty acid synthase cooperates with protrudin to facilitate membrane outgrowth of cellular protrusions. Scientific Reports 2017;7.

20.   Zhang WW, Xu F, Wang D, Ye J, Cai SQ. Buyang Huanwu Decoction ameliorates ischemic stroke by modulating multiple targets with multiple components: In vitro evidences. Chinese Journal of Natural Medicines 2018;16:194-202.

21.   Zhang Z, Xu H, Si L, Chen Y, Zhang B, Wang Y, Wu Y, et al. Construction of an inducible stable cell line for efficient incorporation of unnatural amino acids in mammalian cells. Biochem Biophys Res Commun 2017;489:490-496.

22.   Zhang ZL, Liu RZ, Pu XP, Sun Y, Zhao X. Evaluation of the sub-chronic toxicity of a standardized flavonoid extract of safflower in rats. Regulatory Toxicology and Pharmacology 2017;85:98-107.

23.   Zhu YJ, Gao YQ, Zheng DP, Shui MY, Yu KA, Liu XY, Lin Y, et al. Design and evaluation of EphrinA1 mutants with cerebral protective effect. Scientific Reports 2017;7.

24.   Zhu YJ, Lin Y, Liu XY, Hu WH, Wang YY. Identification of AcAP5 as a novel factor Xa inhibitor with both direct and allosteric inhibition. Biochemical and Biophysical Research Communications 2017;483:495-501.

25.   Zhu YJ, Shui MY, Liu XY, Hu WH, Wang YY. Increased autophagic degradation contributes to the neuroprotection of hydrogen sulfide against cerebral ischemia/reperfusion injury. Metabolic Brain Disease 2017;32:1449-1458.